Table of Contents

A case of true hermaphroditism: presenting as congenital bilateral inguinal hernia

Published on: 20th March, 2023

True hermaphroditism (TH) is a cause of intersexuality in which both ovarian and testicular tissue is present in the same individual [1]. The gonadal distribution in cases of true hermaphroditism varies from [2]
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Subarachnoid hemorrhage in patients without a vascular defect - A retrospective observational study

Published on: 19th April, 2023

Aim: Angiogram-negative subarachnoid hemorrhage (AN-SAH) is defined as subarachnoid hemorrhage with no vascular defect detected in radiological imaging. In approximately 15% of patients with subarachnoid hemorrhage, no visible bleeding cause is found during the initial examination. Our main objective of the study was to analyze epidemiological data and clinical conditions of AN-SAH patients in comparison with patients suffering from subarachnoid hemorrhage caused by a ruptured aneurysm (A-SAH).Methods: This was a single-center retrospective cohort study carried out in Heliodor Święcicki Hospital in Poznań, Poland. All the patients underwent Computed Tomography (CT) scans and Digital Subtraction Angiography (DSA). If no vascular defect was presented, a follow-up after two weeks post-initial examination was suggested. Obtained data were analyzed in Statistica 13.Results: We included 564 patients admitted to the hospital between April 2016 to May 2021 with subarachnoid hemorrhage. 60 of all patients were diagnosed with angiogram-negative subarachnoid hemorrhage (AN-SAH). The average age of the AN-SAH patients group was similar to the A-SAH patients group (53 ± 11.38 vs. 56.8 ± 14.1). Contrary to the A-SAH patients where women were the dominant sex (66.27%), the AN-SAH group comprises mostly men (65%). The clinical condition measured by Hunt Hess (HH) score for both patient groups was more favorable for the AN-SAH group (the median HH score was I) than those of patients with a ruptured aneurysm (the median HH score was II).Conclusion: There is a significant difference between clinical outcome and gender distribution of AN-SAH patients in comparison to A-SAH patients. 
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Single brain metastasis as onset of stage I endometrial carcinoma in patient affected by multiple sclerosis: the first case in literature

Published on: 25th April, 2023

Brain metastases in any gynecological cancer are a rare occurrence. Even more so, it is extremely rare for a gynecological malignancy to manifest itself with symptoms indicative of cerebral involvement. Literature regarding the association between MS and cancer is conflicting. We herein report a rare presentation of single metastasis of endometrial carcinoma in a 59-year-old woman affected by Primary Progressive Multiple Sclerosis (PPMS). A head CT scan was performed, which revealed the presence of an expansive lesion in the left parietal region. After careful assessment, a high-grade endometrial carcinoma was diagnosed and a decision was made to remove both the primary lesion and the brain metastasis in one sitting, through a conjoined surgery session involving neurosurgeons and gynecologists. The postoperative course was free from complications up until a few days after being transferred to a rehabilitation center, where she died following respiratory complications.
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Results of a prospective strategy for focused Minimally Invasive Parathyroidectomy (MIP)

Published on: 3rd May, 2023

Neck exploration for primary HPT is the standard operation in which 4 parathyroid glands are identified and one abnormal parathyroid gland is removed. This is recommended for all patients with primary HPT. We hypothesized that most patients with primary HPT have a single abnormal parathyroid gland (adenoma) and parathyroid imaging studies will identify it and support a focused minimally invasive parathyroidectomy (MIP). This can be combined with ioPTH monitoring making bilateral exploration unnecessary. This paper reports a 93.4% success rate in 249 consecutive prospective patients with primary HPT over a 15-year period with a short operating time and few complications. The findings suggest that this alternate surgical MIP approach should be the procedure of choice for HPT patients.
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